INDICATIONS

Dapoxetine is a selective serotonin reuptake inhibitor that demonstrated efficiency in thousands of male patients with premature ejaculation problem. It increases the levels of serotonin in the brain enhancing the patient's control over ejaculation and having other beneficial effects on sexual life.

INSTRUCTIONS

Use Dapoxetine as directed by your doctor.

• Take Dapoxetine orally with a full glass of water.
• Dapoxetine is usually taken an hour before sexual intercourse.
• Do not take more than the recommended dose or take it more often than once daily.

DOSAGE

For most patients, the starting dose is 60 mg. You may be prescribed Dapoxetine 30 mg or Dapoxetine 60 mg, while some patients may require Dapoxetine 120 mg if they did not respond to the original one.

Ask your health care provider any questions you may have about how to use Dapoxetine.

STORAGE

This medication should be stored at room temperature away from heat, light, and moisture. Keep this medication at a safe place so that your children cannot reach there.

MORE INFO:

Active Ingredient: Dapoxetine hydrochloride.

SAFETY INFORMATION

Do not use Dapoxetine if:

• you are allergic to any ingredient in Dapoxetine
• you have been advised by your doctor to avoid sexual activity because of heart problems
• you are taking nitrates (eg, isosorbide, nitroglycerin) in any form (eg, tablet, capsule, patch, ointment), or nitroprusside
• you use certain recreational drugs called "poppers" (eg, amyl nitrate or nitrite, butyl nitrate or nitrite).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Dapoxetine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a deformed penis (eg, Peyronie disease), blood cell problems (eg, leukemia, sickle cell anemia), or any other condition that may increase the risk of a prolonged erection (priapism)
• if you have a history of a prolonged (more than 4 hours) or painful erection (priapism)
• if you have a history of liver or kidney problems, high or low blood pressure, ulcers, bleeding problems, heart problems (eg, heart failure, irregular heartbeat), or blood vessel problems
• if you have a history of heart attack, stroke, or life-threatening irregular heartbeat, especially within the past 6 months.

Some medicines may interact with Dapoxetine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alpha-blockers (eg, doxazosin), medicines for high blood pressure, nitrates (eg, isosorbide, nitroglycerin), or nitroprusside because severe low blood pressure with dizziness, lightheadedness, and fainting may occur
• Azole antifungals (eg, itraconazole, ketoconazole), H₂ antagonists (eg, cimetidine), HIV protease inhibitors (eg, ritonavir, saquinavir), macrolide antibiotics (eg, erythromycin), narcotic analgesics (eg, dihydrocodeine), or telithromycin because they may increase the risk of Dapoxetine's side effects
• Bosentan or rifampin because they may decrease Dapoxetine's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dapoxetine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

• Dapoxetine may cause dizziness, drowsiness, fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Dapoxetine with caution. Do not drive or perform other possible unsafe